Sodium citrate dihydrate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

二水柠檬酸钠是一种抗凝血剂，也用作缓冲剂和食品防腐剂。

Sodium citrate dihydrate is an anticoagulant, and also used as a buffer and food preservatives.

Cell Viability Assay Cell Line:MGC-803 Concentration:1.25, 2.5, 5, 10,15, 20, 30, 40, 60 mM Incubation Time:24, 48 h Result:Decreased cell viability in a dose-and time-dependent manner.The IC50 value is 10.08 mM after 48 h.Apoptosis Analysis Cell Line:MGC-803 Concentration:5, 10, 20 mM Incubation Time:24 h Result:Decreased the mRNA and protein expressions of anti-apoptotic Bcl-2 and Survivin.Increased the mRNA and protein expression level of proapoptotic Bax, caspase-3 and Cyt-c.Western Blot Analysis Cell Line:MGC-803Concentration:5, 10, 20 mM Incubation Time:24, 48 h Result:Induced cell apoptosis in a dose-and time-dependent manner.Increased the G2/M phase arrest.

Animal Model:Adenine-Induced Chronic Renal Failure Rat ModelDosage:216, 746 mg/kg Administration: i.g.Result:Decreased the expression of renal fibrosis-related proteins TGF-β1 and CIV.Decreased the expression of PERK, ATF6 and CHOP.

Trisodium citrate dihydrate | Citric acid trisodium salt dihydrate

GPCR/G Protein

Antibacterial

Bacterial

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6132-04-3

294.1

C6H9Na3O9

>98% (HPLC)

H2O:125 mg/mL (425.03 mM; Need ultrasonic)

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.[Na+].[Na+].[Na+]

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(-20℃)

With Ice Pack

≥ 2 years